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The Chromatin Remodeling Component Arid1a Is a Suppressor of Spontaneous Mammary Tumors in Mice

Human cancer genome studies have identified the SWI/SNF chromatin remodeling complex member ARID1A as one of the most frequently altered genes in several tumor types. Its role as an ovarian tumor suppressor has been supported in compound knockout mice. Here, we provide genetic and functional evidenc...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Kartha, Nithya, Shen, Lishuang, Maskin, Carolyn, Wallace, Marsha, Schimenti, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981264/
https://ncbi.nlm.nih.gov/pubmed/27280691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.184879
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