Antileukemic and immunosuppressive activity of 2-chloro-2'-deoxyadenosine.

The adenosine deaminase-resistant purine deoxynucleoside 2-chloro-2'-deoxyadenosine (CdA) is markedly toxic in vitro to nondividing and proliferating normal human lymphocytes and to many leukemia cell specimens. The CdA is also effective against mouse L1210 leukemia in vivo. The present investigatio...

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Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Carson, D A, Wasson, D B, Beutler, E
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1984
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6585795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.7.2232
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