Antileukemic and immunosuppressive activity of 2-chloro-2'-deoxyadenosine.

The adenosine deaminase-resistant purine deoxynucleoside 2-chloro-2'-deoxyadenosine (CdA) is markedly toxic in vitro to nondividing and proliferating normal human lymphocytes and to many leukemia cell specimens. The CdA is also effective against mouse L1210 leukemia in vivo. The present investigatio...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Carson, D A, Wasson, D B, Beutler, E
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1984
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6585795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.7.2232
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