Antileukemic and immunosuppressive activity of 2-chloro-2'-deoxyadenosine.
The adenosine deaminase-resistant purine deoxynucleoside 2-chloro-2'-deoxyadenosine (CdA) is markedly toxic in vitro to nondividing and proliferating normal human lymphocytes and to many leukemia cell specimens. The CdA is also effective against mouse L1210 leukemia in vivo. The present investigatio...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1984
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6585795/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.7.2232 |
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