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Increased Expression of the dsRNA-Activated Protein Kinase PKR in Breast Cancer Promotes Sensitivity to Doxorubicin

It has been reported that the expression and activity of the interferon-inducible, dsRNA-dependent protein kinase, PKR, is increased in mammary carcinoma cell lines and primary tumor samples. To extend these findings and determine how PKR signaling may affect breast cancer cell sensitivity to chemot...

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Hlavní autoři: Bennett, Richard L., Carruthers, Aubrey L., Hui, Teng, Kerney, Krystal R., Liu, Xiangfei, May, W. Stratford
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454339/
https://ncbi.nlm.nih.gov/pubmed/23029376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046040
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