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Regulation of hTERT transcription: a target of cellular and viral mechanisms for immortalization and carcinogenesis

A hallmark of human cancer cells is immortal cell growth, which is associated with telomere maintenance by telomerase. The transcriptional regulation of the human telomerase reverse transcriptase (hTERT) gene is a major mechanism that negatively and positively controls telomerase activity in normal...

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Hlavní autoři: Horikawa, Izumi, Michishita, Eriko, Barrett, J. Carl
Médium: Artigo
Jazyk:Inglês
Vydáno: Kluwer Academic Publishers 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449964/
https://ncbi.nlm.nih.gov/pubmed/19003240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-004-5122-4
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