Transcriptional Activation of the Telomerase hTERT Gene by Human Papillomavirus Type 16 E6 Oncoprotein

The E6 and E7 oncogenes of human papillomavirus type 16 (HPV-16) are sufficient for the immortalization of human genital keratinocytes in vitro. The products of these viral genes associate with p53 and pRb tumor suppressor proteins, respectively, and interfere with their normal growth-regulatory fun...

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Hlavní autoři: Veldman, Tim, Horikawa, Izumi, Barrett, J. Carl, Schlegel, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114198/
https://ncbi.nlm.nih.gov/pubmed/11287602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.9.4467-4472.2001
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