Lysine-specific demethylase 1 (LSD1) Is required for the transcriptional repression of the telomerase reverse transcriptase (hTERT) gene.

BACKGROUND: Lysine-specific demethylase 1 (LSD1), catalysing demethylation of mono- and di-methylated histone H3-K4 or K9, exhibits diverse transcriptional activities by mediating chromatin reconfiguration. The telomerase reverse transcriptase (hTERT) gene, encoding an essential component for telome...

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Principais autores:	Qingjun Zhu, Cheng Liu, Zheng Ge, Xiaolei Fang, Xi Zhang, Klas Strååt, Magnus Björkholm, Dawei Xu
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2008-01-01
Serija:	PLoS ONE
Online dostop:	http://europepmc.org/articles/PMC2180196?pdf=render
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