Transcriptional Activation of the Telomerase hTERT Gene by Human Papillomavirus Type 16 E6 Oncoprotein

The E6 and E7 oncogenes of human papillomavirus type 16 (HPV-16) are sufficient for the immortalization of human genital keratinocytes in vitro. The products of these viral genes associate with p53 and pRb tumor suppressor proteins, respectively, and interfere with their normal growth-regulatory fun...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Veldman, Tim, Horikawa, Izumi, Barrett, J. Carl, Schlegel, Richard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114198/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287602/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.9.4467-4472.2001
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