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Dialysis cultures with immobilized hybridoma cells for effective production of monoclonal antibodies
An industrial scale reactor concept for continuous cultivation of immobilized animal cells (e.g. hybridoma cells) in a radial-flow fixed bed is presented, where low molecular weight metabolites are removed via dialysis membrane and high molecular products (e.g. monoclonal antibodies) are enriched. I...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Kluwer Academic Publishers
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449882/ https://ncbi.nlm.nih.gov/pubmed/22358519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1007911517505 |
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