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Influence of bcl-2 on antibody productivity in high cell density perfusion cultures of hybridoma

Apoptosis is an active, genetically determined death mechanism which can be induced by a wide range of physiological factors and by mild stress. It is the predominant form of cell death during the production of antibodies from murine hybridoma cell lines. A number of studies have now demonstrated th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fassnacht, D., Rössing, S., Singh, R. P., Al-Rubeai, M., Pörtner, R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Kluwer Academic Publishers 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449950/
https://ncbi.nlm.nih.gov/pubmed/19003359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008055702079
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