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Variable functions of bcl-2 in mediating bioreactor stress- induced apoptosis in hybridoma cells
It has been demonstrated that the cell lines used for production of biopharmaceuticals are highly susceptible to apoptosis, and that over-expression of the bcl-2 oncogene can protect cells from death. Stress associated with the deprivation of nutrients has been shown to be the main cause of apoptosi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Kluwer Academic Publishers
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449844/ https://ncbi.nlm.nih.gov/pubmed/19003419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1008002319400 |
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