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Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity

More than half of the known protein tyrosine phosphatases (PTPs) in the human genome are expressed in T cells, and significant progress has been made in elucidating the biology of these enzymes in T-cell development and function. Here we provide a systematic review of the current understanding of th...

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Autori principali: Stanford, Stephanie M, Rapini, Novella, Bottini, Nunzio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449242/
https://ncbi.nlm.nih.gov/pubmed/22862552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03591.x
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