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Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease
Inheritance of a coding variant of the protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene is associated with increased susceptibility to autoimmunity and infection. Efforts to elucidate the mechanisms whereby the PTPN22-C1858T variant modulates disease risk revealed that PTPN22 exerts s...
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| Publicado no: | Annu Rev Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6402334/ https://ncbi.nlm.nih.gov/pubmed/24364806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-032713-120249 |
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