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Modulation of TCR Signaling by Tyrosine Phosphatases: From Autoimmunity to Immunotherapy
Early TCR signaling is dependent on rapid phosphorylation and dephosphorylation of multiple signaling and adaptor proteins, leading to T cell activation. This process is tightly regulated by an intricate web of interactions between kinases and phosphatases. A number of tyrosine phosphatases have bee...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793860/ https://ncbi.nlm.nih.gov/pubmed/33425916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.608747 |
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