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Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S
Proteolytic processing of the amiloride-sensitive epithelial sodium channel (ENaC) by serine proteases is known to be important for channel activation. Inappropriate ENaC activation by proteases may contribute to the pathophysiology of cystic fibrosis and could be involved in sodium retention and th...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer-Verlag
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448907/ https://ncbi.nlm.nih.gov/pubmed/22864553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1138-3 |
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