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Activation of the Human Epithelial Sodium Channel (ENaC) by Bile Acids Involves the Degenerin Site

The epithelial sodium channel (ENaC) is a member of the ENaC/degenerin ion channel family, which also includes the bile acid-sensitive ion channel (BASIC). So far little is known about the effects of bile acids on ENaC function. ENaC is probably a heterotrimer consisting of three well characterized...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Ilyaskin, Alexandr V., Diakov, Alexei, Korbmacher, Christoph, Haerteis, Silke
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025673/
https://ncbi.nlm.nih.gov/pubmed/27489102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726471
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