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α6 nAChR subunit residues that confer α-conotoxin BuIA selectivity

Nicotinic acetylcholine receptors (nAChRs) containing α6 and/or α4 subunits modulate the release of dopamine. However, few compounds can effectively discriminate between ligand-binding sites that contain α6 vs. α4 nAChR subunits. Using a chimeric (α6/α4) subunit, we showed that α-conotoxin BuIA bind...

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Bibliografske podrobnosti
Main Authors: Kim, Hyun-Woo, McIntosh, J. Michael
Format: Artigo
Jezik:Inglês
Izdano: Federation of American Societies for Experimental Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448775/
https://ncbi.nlm.nih.gov/pubmed/22751014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-204487
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