Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics

BACKGROUND: α-Conotoxins have exciting therapeutic potential based on their high selectivity and affinity for nicotinic acetylcholine receptors. The spacing between the cysteine residues in α-conotoxins is variable, leading to the classification of sub-families. BuIA is the only α-conotoxin containi...

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Detalhes bibliográficos
Main Authors: Jin, Ai-Hua, Brandstaetter, Hemma, Nevin, Simon T, Tan, Chia Chia, Clark, Richard J, Adams, David J, Alewood, Paul F, Craik, David J, Daly, Norelle L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865545/
https://ncbi.nlm.nih.gov/pubmed/17445276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-28
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