Influence of Disulfide Connectivity on Structure and Bioactivity of α-Conotoxin TxIA

Cone snails express a sophisticated arsenal of small bioactive peptides known as conopeptides or conotoxins (CTxs). Through evolutionary selection, these peptides have gained the ability to interact with a range of ion channels and receptors, such as nicotinic acetylcholine receptors (nAChRs). Here,...

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Bibliographic Details
Published in:Molecules
Main Authors: Wu, Yong, Wu, Xiaosa, Yu, Jinpeng, Zhu, Xiaopeng, Zhangsun, Dongting, Luo, Sulan
Format: Artigo
Language:Inglês
Published: MDPI 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6271783/
https://ncbi.nlm.nih.gov/pubmed/24434670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules19010966
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