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DSPE-PEG Modification of α-Conotoxin TxID
In order to improve stability of a peptide marine drug lead, α-conotoxin TxID, we synthesized and modified TxID at the N-terminal with DSPE-PEG-NHS by a nucleophilic substitution reaction to prepare the DSPE-PEG-TxID for the first time. The reaction conditions, including solvent, ratio, pH, and reac...
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| Publicado no: | Mar Drugs |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6627868/ https://ncbi.nlm.nih.gov/pubmed/31181805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17060342 |
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