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α-Conotoxin TxID and [S9K]TxID, α3β4 nAChR Antagonists, Attenuate Expression and Reinstatement of Nicotine-Induced Conditioned Place Preference in Mice

Tobacco smoking has become a prominent health problem faced around the world. The α3β4 nicotinic acetylcholine receptor (nAChR) is strongly associated with nicotine reward and withdrawal symptom. α-Conotoxin TxID, cloned from Conus textile, is a strong α3β4 nAChR antagonist, which has weak inhibitio...

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Bibliographic Details
Published in:Mar Drugs
Main Authors: Li, Xiaodan, You, Shen, Xiong, Jian, Qiao, Yamin, Yu, Jinpeng, Zhangsun, Dongting, Luo, Sulan
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7765617/
https://ncbi.nlm.nih.gov/pubmed/33339145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md18120646
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