Comparison of the complete nucleotide sequences of the genomes of the neurovirulent poliovirus P3/Leon/37 and its attenuated Sabin vaccine derivative P3/Leon 12a1b.

As part of a study into the molecular basis of attenuation and reversion to neurovirulence in the Sabin poliovirus vaccines, we have determined the complete nucleotide sequence of a cloned DNA copy of the genome of P3/Leon/37, the neurovirulent progenitor of the type 3 Sabin vaccine strain, P3/Leon...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Stanway, G, Hughes, P J, Mountford, R C, Reeve, P, Minor, P D, Schild, G C, Almond, J W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324200/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.5.1539
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