Nucleotide sequence of a neurovirulent variant of the type 2 oral poliovirus vaccine.

Infectious cDNAs of the Sabin type 2 poliovirus vaccine virus and a vaccine-derived neurovirulent type 2 strain (P2/117) have been cloned in Escherichia coli. Nucleotide sequence analysis revealed that P2/117 differs from the vaccine strain by just 23 point mutations. Three occur in the 5' noncoding...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Pollard, S R, Dunn, G, Cammack, N, Minor, P D, Almond, J W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC251143/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2552175/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.11.4949-4951.1989
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