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Comparison of the complete nucleotide sequences of the genomes of the neurovirulent poliovirus P3/Leon/37 and its attenuated Sabin vaccine derivative P3/Leon 12a1b.

As part of a study into the molecular basis of attenuation and reversion to neurovirulence in the Sabin poliovirus vaccines, we have determined the complete nucleotide sequence of a cloned DNA copy of the genome of P3/Leon/37, the neurovirulent progenitor of the type 3 Sabin vaccine strain, P3/Leon...

詳細記述

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書誌詳細
主要な著者: Stanway, G, Hughes, P J, Mountford, R C, Reeve, P, Minor, P D, Schild, G C, Almond, J W
フォーマット: Artigo
言語:Inglês
出版事項: 1984
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC344872/
https://ncbi.nlm.nih.gov/pubmed/6324200
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