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Quantitative Analysis of the Mutagenic Potential of 1-Aminopyrene-DNA Adduct Bypass Catalyzed by Y-Family DNA Polymerases

N- (deoxyguanosin-8-yl)-1-aminopyrene (dG(AP)) is the predominant nitro polyaromatic hydrocarbon product generated from the air pollutant 1-nitropyrene reacting with DNA. Previous studies have shown that dG(AP) induces genetic mutations in bacterial and mammalian cells. One potential source of these...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sherrer, Shanen M., Taggart, David J., Pack, Lindsey R., Malik, Chanchal K., Basu, Ashis K., Suo, Zucai
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448278/
https://ncbi.nlm.nih.gov/pubmed/22917544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2012.08.002
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