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Transcription factor Foxp3 and its protein partners form a complex regulatory network

The transcription factor Foxp3 is indispensible for the differentiation and function of regulatory T cells (T(reg) cells). To gain insights into the molecular mechanisms of Foxp-mediated gene expression we purified Foxp3 complexes and explored their composition. Biochemical and mass-spectrometric an...

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Библиографические подробности
Главные авторы: Rudra, Dipayan, deRoos, Paul, Chaudhry, Ashutosh, Niec, Rachel, Arvey, Aaron, Samstein, Robert M., Leslie, Christina, Shaffer, Scott A., Goodlett, David R., Rudensky, Alexander Y.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448012/
https://ncbi.nlm.nih.gov/pubmed/22922362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2402
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