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Runx-CBFβ complexes control Foxp3 expression in regulatory T cells
Foxp3 plays an indispensable role in establishing stable transcriptional and functional programs of regulatory T (T(reg)) cells. Loss of Foxp3 expression in mature T(reg) cells results in a failure of suppressor function, yet the molecular mechanisms ensuring steady heritable Foxp3 expression in the...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764816/ https://ncbi.nlm.nih.gov/pubmed/19767756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1795 |
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