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Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3(+) inducible regulatory T cells
Forkhead box P3 (FOXP3)(+)CD4(+)CD25(+) inducible regulatory T (iT reg) cells play an important role in immune tolerance and homeostasis. In this study, we show that the transforming growth factor-β (TGF-β) induces the expression of the Runt-related transcription factors RUNX1 and RUNX3 in CD4(+) T...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806624/ https://ncbi.nlm.nih.gov/pubmed/19917773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090596 |
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