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Transcription factors RUNX1 and RUNX3 in the induction and suppressive function of Foxp3(+) inducible regulatory T cells

Forkhead box P3 (FOXP3)(+)CD4(+)CD25(+) inducible regulatory T (iT reg) cells play an important role in immune tolerance and homeostasis. In this study, we show that the transforming growth factor-β (TGF-β) induces the expression of the Runt-related transcription factors RUNX1 and RUNX3 in CD4(+) T...

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Detalhes bibliográficos
Main Authors: Klunker, Sven, Chong, Mark M.W., Mantel, Pierre-Yves, Palomares, Oscar, Bassin, Claudio, Ziegler, Mario, Rückert, Beate, Meiler, Flurina, Akdis, Mübeccel, Littman, Dan R., Akdis, Cezmi A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806624/
https://ncbi.nlm.nih.gov/pubmed/19917773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090596
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