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Transcription factor Foxp1 regulates Foxp3 chromatin binding and maintains regulatory T cell function
Regulatory T (T(reg) ) cells, whose differentiation and function are controlled by transcription factor Foxp3, express high amounts of a closely related family member Foxp1. Here we explored Foxp1 function in T(reg) cells. We found that a large number of Foxp3-bound genomic sites in T(reg) cells wer...
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| Izdano u: | Nat Immunol |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7534899/ https://ncbi.nlm.nih.gov/pubmed/30643266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0291-z |
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