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NMR characterization of Immunoglobulin G Fc glycan motion on enzymatic sialylation
The terminal carbohydrate residues of the N-glycan on the immunoglobulin G (IgG) Fragment crystalizable (Fc) determine whether IgG activates pro- or anti-inflammatory receptors. The IgG Fc alone becomes potently anti-inflammatory upon addition of α2–6 linked N-acetylneuraminic acid residues to the N...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447994/ https://ncbi.nlm.nih.gov/pubmed/22574931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300319q |
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