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Branch Specific Sialylation of IgG-Fc Glycans by ST6Gal-I

Sialylated forms of the Fc fragment of immunoglobulin G, produced by the human α2–6 sialyltransferase ST6Gal-I, were identified as potent anti-inflammatory mediators in a mouse model of rheumatoid arthritis and are potentially the active components in IVIG therapies. The activities and specificities...

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Autores principales: Barb, Adam W., Brady, Evan K., Prestegard, James H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761508/
https://ncbi.nlm.nih.gov/pubmed/19772356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901430h
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