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Impact of Fc N-glycan sialylation on IgG structure
Human IgG antibodies containing terminal alpha 2,6-linked sialic acid on their Fc N-glycans have been shown to reduce antibody-dependent cell-mediated cytotoxicity and possess anti-inflammatory properties. Although terminal sialylation on complex N-glycans can happen via either an alpha 2,3-linkage...
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| Publicado no: | MAbs |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6816437/ https://ncbi.nlm.nih.gov/pubmed/31411531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1655377 |
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