Llwytho...
Long-range effects of familial hypertrophic cardiomyopathy mutations E180G and D175N on the properties of tropomyosin
Cardiac α-tropomyosin (Tm) single site mutations, D175N and E180G, cause familial hypertrophic cardiomyopathy (FHC). Previous studies have shown that these mutations increase both Ca(2+)-sensitivity and residual contractile activity at low Ca(2+), which causes incomplete relaxation during diastole r...
Wedi'i Gadw mewn:
| Prif Awduron: | , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2012
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3447992/ https://ncbi.nlm.nih.gov/pubmed/22794249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3006835 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|