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Interferon Regulatory Factor-8 Is Important for Histone Deacetylase Inhibitor-Mediated Antitumor Activity

The notion that epigenetic alterations in neoplasia are reversible has provided the rationale to identify epigenetic modifiers for their ability to induce or enhance tumor cell death. Histone deacetylase inhibitors (HDACi) represent one such class of anti-neoplastic agents. Despite great interest fo...

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Detalhes bibliográficos
Main Authors: Banik, Debarati, Khan, A. Nazmul H., Walseng, Even, Segal, Brahm H., Abrams, Scott I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446900/
https://ncbi.nlm.nih.gov/pubmed/23028998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045422
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