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Histone deacetylase regulation of immune gene expression in tumor cells

Epigenetic modifications of chromatin, such as histone acetylation, are involved in repression of tumor antigens and multiple immune genes that are thought to facilitate tumor escape. The status of acetylation in a cell is determined by the balance of the activities of histone acetyltransferases and...

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Bibliographic Details
Main Authors: Khan, A. Nazmul H., Tomasi, Thomas B.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131781/
https://ncbi.nlm.nih.gov/pubmed/18213528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-007-0085-0
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