The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

Antigen-presenting cells (APCs) induce T cell activation as well as T cell tolerance. The molecular basis of the regulation of this critical ‘decision’ is not well understood. Here we show that HDAC11, a member of the HDAC histone deacetylase family with no prior defined physiological function, nega...

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Bibliographische Detailangaben
Hauptverfasser: Villagra, Alejandro, Cheng, Fengdong, Wang, Hong-Wei, Suarez, Ildelfonso, Glozak, Michelle, Maurin, Michelle, Nguyen, Danny, Wright, Kenneth L, Atadja, Peter W, Bhalla, Kapil, Pinilla-Ibarz, Javier, Seto, Edward, Sotomayor, Eduardo M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925685/
https://ncbi.nlm.nih.gov/pubmed/19011628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1673
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