The Lysophosphatidic Acid Type 2 Receptor Is Required for Protection Against Radiation-Induced Intestinal Injury

BACKGROUND & AIMS: We recently identified lysophosphatidic acid (LPA) as a potent antiapoptotic agent for the intestinal epithelium. The objective of the present study was to evaluate the effect of octadecenyl thiophosphate (OTP), a novel rationally designed, metabolically stabilized LPA mimic,...

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Autori principali: Deng, Wenlin, Shuyu, E, Tsukahara, Ryoko, Valentine, William J., Durgam, Gangadhar, Gududuru, Veeresa, Balazs, Louisa, Manickam, Venkatraman, Arsura, Marcello, Vanmiddlesworth, Lester, Johnson, Leonard R., Parrill, Abby L., Miller, Duane D., Tigyi, Gabor
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446791/
https://ncbi.nlm.nih.gov/pubmed/17484878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.03.038
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