Mitigation of the Hematopoietic and Gastrointestinal Acute Radiation Syndrome by Octadecenyl Thiophosphate, a Small Molecule Mimic of Lysophosphatidic Acid

We have previously demonstrated that the small molecule octadecenyl thiophosphate (OTP), a synthetic mimic of the growth factor-like mediator lysophosphatidic acid (LPA), showed radioprotective activity in a mouse model of total-body irradiation (TBI) when given orally or intraperitoneally 30 min be...

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Vydáno v:Radiat Res
Hlavní autoři: Deng, Wenlin, Kimura, Yasuhiro, Gududuru, Veeresh, Wu, Wenjie, Balogh, Andrea, Szabo, Erzsebet, Thompson, Karin Emmons, Yates, C. Ryan, Balazs, Louisa, Johnson, Leonard R., Miller, Duane D., Strobos, Jur, McCool, W. Shannon, Tigyi, Gabor J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428663/
https://ncbi.nlm.nih.gov/pubmed/25807318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13830.1
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