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Identification of the Hydrophobic Ligand Binding Pocket of the S1P(1) Receptor
Sphingosine 1-phosphate (S1P), a naturally occurring sphingolipid mediator and also a second messenger with growth factor-like actions in almost every cell type, is an endogenous ligand of five G protein-coupled receptors (GPCRs) in the endothelial differentiation gene family. The lack of GPCR cryst...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3446783/ https://ncbi.nlm.nih.gov/pubmed/17114791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609648200 |
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