Identification of the Hydrophobic Ligand Binding Pocket of the S1P(1) Receptor

Sphingosine 1-phosphate (S1P), a naturally occurring sphingolipid mediator and also a second messenger with growth factor-like actions in almost every cell type, is an endogenous ligand of five G protein-coupled receptors (GPCRs) in the endothelial differentiation gene family. The lack of GPCR cryst...

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Hlavní autoři: Fujiwara, Yuko, Osborne, Daniel A., Walker, Michelle D., Wang, De-an, Bautista, Debra A., Liliom, Karoly, Van Brocklyn, James R., Parrill, Abby L., Tigyi, Gabor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446783/
https://ncbi.nlm.nih.gov/pubmed/17114791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M609648200
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