Interactions of High-Affinity Cationic Blockers with the Translocation Pores of B. anthracis, C. botulinum, and C. perfringens Binary Toxins

Cationic β-cyclodextrin derivatives were recently introduced as highly effective, potentially universal blockers of three binary bacterial toxins: anthrax toxin of Bacillus anthracis, C2 toxin of Clostridium botulinum, and iota toxin of Clostridium perfringens. The binary toxins are made of two sepa...

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Hlavní autoři: Bezrukov, Sergey M., Liu, Xian, Karginov, Vladimir A., Wein, Alexander N., Leppla, Stephen H., Popoff, Michel R., Barth, Holger, Nestorovich, Ekaterina M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2012
Témata:
Channels and Transporters
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446695/
https://ncbi.nlm.nih.gov/pubmed/22995493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.07.050
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