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Exploring the Nature of Cationic Blocker Recognition by the Anthrax Toxin Channel

Obstructing conductive pathways of the channel-forming toxins with targeted blockers is a promising drug design approach. Nearly all tested positively charged ligands have been shown to reversibly block the cation-selective channel-forming protective antigen (PA(63)) component of the binary anthrax...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Momben Abolfath, Sanaz, Kolberg, Michelle, Karginov, Vladimir A., Leppla, Stephen H., Nestorovich, Ekaterina M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838753/
https://ncbi.nlm.nih.gov/pubmed/31587826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.041
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