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New Preorganized γ-Amino Acids as Foldamer Building Blocks
[Image: see text] An asymmetric synthesis of two new diastereomeric γ-amino acids is described. Both molecules contain a cyclohexyl ring to limit conformational flexibility about the Cα-C(β) bond; they differ in having cis vs. trans stereochemistry on the ring. Residues derived from the cis γ isomer...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445736/ https://ncbi.nlm.nih.gov/pubmed/22568480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol3008815 |
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