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Helix Formation in Preorganized β/γ-Peptide Foldamers: Hydrogen-Bond Analogy to the α-Helix without α-Amino Acid Residues

We report the first high-resolution structural data for the β/γ-peptide 13-helix (i,i+3 C=O···H-N H-bonds), a secondary structure that is formed by oligomers with a 1:1 alternation of β- and γ-amino acid residues. Our characterization includes both crystallophaphic and 2D NMR data. Previous studies...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guo, Li, Almeida, Aaron M., Zhang, Weicheng, Reidenbach, Andrew G., Choi, Soo Hyuk, Guzei, Ilia A., Gellman, Samuel H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904518/
https://ncbi.nlm.nih.gov/pubmed/20491510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103233a
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