Characteristic Structural Parameters for the γ-Peptide 14-Helix:Importance of Subunit Preorganization

[Image: see text] We report crystallographic data for a set of homologous γ-peptides that contain a Boc-protected residue derived from the flexible gabapentin monomer at the N-terminus and cyclically constrained γ-residues at all other positions. The crystallized γ-peptides range in length from 3 to...

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Autors principals: Guo, Li, Zhang, Weicheng, Reidenbach, Andrew G., Giuliano, Michael W., Guzei, Ilia A., Spenser, Lara C., Gellman, Samuel H.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429132/
https://ncbi.nlm.nih.gov/pubmed/21567680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201101301
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