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Pancreatic β-Cell Dedifferentiation As Mechanism Of Diabetic β-Cell Failure
Diabetes is associated with β-cell failure. But it remains unclear whether the latter results from reduced β-cell number or function. FoxO1 integrates β-cell proliferation with adaptive β-cell function. We interrogated the contribution of these two processes to β-cell dysfunction, using mice lacking...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445031/ https://ncbi.nlm.nih.gov/pubmed/22980982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.07.029 |
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