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Legacy Effect of Foxo1 in Pancreatic Endocrine Progenitors on Adult β-Cell Mass and Function

β-Cell dysfunction in diabetes results from abnormalities of insulin production, secretion, and cell number. These abnormalities may partly arise from altered developmental programming of β-cells. Foxo1 is important to maintain adult β-cells, but little is known about its role in pancreatic progenit...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Talchai, Shivatra Chutima, Accili, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512230/
https://ncbi.nlm.nih.gov/pubmed/25784544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1696
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