Laddar...
Generation Of Functional Insulin-Producing Cells In The Gut By Foxo1 Ablation
Restoration of regulated insulin secretion is the ultimate goal of type 1 diabetes therapy. Here we show that, surprisingly, somatic ablation of Foxo1 in Neurog3(+) enteroendocrine progenitor cells gives rise to gut insulin-positive cells (Ins(+)) that express markers of mature β-cells, and secrete...
Sparad:
| Huvudupphovsmän: | , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2012
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315609/ https://ncbi.nlm.nih.gov/pubmed/22406641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2215 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|