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Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes
CONTEXT: Diabetes is associated with a deficit of insulin-producing β-cells. Animal studies show that β-cells become dedifferentiated in diabetes, reverting to a progenitor-like stage, and partly converting to other endocrine cell types. OBJECTIVE: To determine whether similar processes occur in hum...
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Gepubliceerd in: | J Clin Endocrinol Metab |
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Hoofdauteurs: | , , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Endocrine Society
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4803182/ https://ncbi.nlm.nih.gov/pubmed/26713822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-2860 |
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